Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.65 |
| ▸ | SCD | O00767 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947460 | 1.00 | HSD17B10 (0.73) | HSD17B10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL12717675 | 0.92 | NPC1 (0.81) | HSD17B10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14807662 | 0.92 | MAP3K5 (0.70) | HSD17B10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL24729344 | 0.92 | NPC1 (0.67) | HSD17B10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL16554035 | 0.90 | HSD17B1 (0.76) | HSD17B10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL16562169 | 0.89 | NPC1 (0.73) | HSD17B10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL24729512 | 0.88 | HSD17B10 (0.63) | HSD17B10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29947777 | 0.88 | HSD17B10 (0.63) | HSD17B10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL24729223 | 0.88 | HSD17B10 (0.65) | HSD17B10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL24729560 | 0.88 | HSD17B10 (0.65) | HSD17B10NPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |