Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23938021 | 0.81 | OGA (0.37) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL21704223 | 0.79 | OGA (0.33) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL23938318 | 0.76 | — | — | |
| SCHEMBL24159068 | 0.74 | SMN1; SMN2 (0.39) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL24158913 | 0.74 | SMN1; SMN2 (0.39) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL24730369 | 0.70 | OGA (0.34) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL30059739 | 0.68 | GBA1 (0.41) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL20731043 | 0.68 | GBA1 (0.41) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL18970541 | 0.64 | OGA (0.41) | OGA | |
| SCHEMBL20244201 | 0.64 | OGA (0.41) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | VALO HEALTH, INC. (US) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | USP28, USP25, USP24 | OGA 1062/4885SMN1; SMN2 2918/4885NPSR1 4125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.