SCHEMBL24730477

SCHEMBL24730477

COC(=O)c1ccc(NC(=O)OC(C)(C)C)c(F)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATR Q13535 1/20 0.46
KDM4E B2RXH2 3/20 0.39
HPGD P15428 3/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP17A1 P05093 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
KCNQ4 P56696 3/20 0.38
KCNQ5 Q9NR82 3/20 0.38
PTGER4 P35408 1/20 0.38
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
ATM Q13315 1/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPC1 O15118 1/20 0.35
CASP3 P42574 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30641929 1.00 ATR (0.46) ATRKDM4EHPGDALDH1A1CYP1A2
SCHEMBL30641931 0.87 CYP17A1 (0.40) ATRCYP17A1RXFP1KCNQ4KCNQ5
SCHEMBL24731578 0.87 CYP17A1 (0.40) ATRCYP17A1RXFP1KCNQ4KCNQ5
SCHEMBL30739735 0.82 CYP17A1 (0.44) HPGDCYP17A1RXFP1KCNQ4KCNQ5
SCHEMBL30464227 0.82 RXFP1 (0.50) ATRKDM4EHPGDALDH1A1CYP1A2
SCHEMBL3771942 0.82 RXFP1 (0.50) ATRKDM4EHPGDALDH1A1CYP1A2
SCHEMBL31303022 0.82 ATR (0.43) ATRKDM4EHPGDALDH1A1CYP1A2
SCHEMBL31455160 0.80 CYP17A1 (0.43) CYP17A1RXFP1KCNQ4KCNQ5LMNA
SCHEMBL28476853 0.80 KDM4E (0.51) ATRKDM4EHPGDALDH1A1CYP1A2
SCHEMBL16257042 0.78 KDM4E (0.51) ATRKDM4EHPGDALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117098750-A Molecules having pesticidal utility, and intermediates and methods related thereto 科迪华农业科技有限责任公司 2023-11-21 CN disclosed
WO-2022204080-A1 MOLECULES HAVING PESTICIDAL UTILITY AND INTERMEDIATES AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2022-09-29 WO disclosed