Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476492 | 0.84 | NOS3 (0.36) | OPRL1 | |
| SCHEMBL2470462 | 0.84 | NOS3 (0.36) | OPRL1 | |
| SCHEMBL15387102 | 0.83 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL2475137 | 0.81 | TNKS2 (0.33) | OPRL1 | |
| SCHEMBL4247676 | 0.71 | — | — | |
| SCHEMBL5574130 | 0.71 | — | — | |
| SCHEMBL2470559 | 0.70 | NOS3 (0.36) | OPRL1 | |
| SCHEMBL2474035 | 0.68 | OPRL1 (0.34) | OPRL1 | |
| SCHEMBL26511990 | 0.68 | OPRL1 (0.39) | OPRL1 | |
| SCHEMBL2470093 | 0.68 | OPRL1 (0.34) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374804-A1 | Chemokine receptor binding heterocyclic compounds with enhanced efficacy | Genzyme Corporation (US) | 2011-10-12 | — | — | EP | disclosed |