Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | HUWE1 | Q7Z6Z7 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29977645 | 1.00 | MC4R (0.46) | MC4RAPPKDM4EMAPTMAPK1 | |
| SCHEMBL24732588 | 0.91 | ACP1 (0.46) | APPKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL29809445 | 0.91 | ACP1 (0.46) | APPKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL29976921 | 0.90 | HRH3 (0.46) | APPKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL24732723 | 0.90 | HRH3 (0.46) | APPKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL24733471 | 0.88 | ACP1 (0.47) | APPKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL29976948 | 0.88 | ACP1 (0.47) | APPKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL24733480 | 0.84 | EGFR (0.45) | MC4RKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL29809290 | 0.84 | EGFR (0.45) | MC4RKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL24732593 | 0.83 | ACHE (0.45) | MAPTSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161420-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |