Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23102986 | 0.88 | LMNA (0.38) | LMNACYP2C9 | |
| SCHEMBL21145789 | 0.88 | LMNA (0.38) | LMNACYP2C9 | |
| SCHEMBL16021834 | 0.88 | LMNA (0.38) | LMNACYP2C9 | |
| SCHEMBL23103256 | 0.88 | LMNA (0.38) | LMNACYP2C9 | |
| SCHEMBL23102961 | 0.88 | LMNA (0.38) | LMNACYP2C9 | |
| SCHEMBL23103254 | 0.88 | LMNA (0.38) | LMNACYP2C9 | |
| SCHEMBL19788244 | 0.79 | KDM4E (0.30) | — | |
| SCHEMBL29296256 | 0.78 | PIK3CD (0.37) | LMNACYP2C9DPP4DPP7 | |
| SCHEMBL681681 | 0.78 | — | — | |
| SCHEMBL9963376 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256459-A1 | KRAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2022-12-08 | — | — | WO | disclosed |