Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | POLA1 | P09884 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | POLG | P54098 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19236725 | 0.90 | PDE3A (0.49) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL22739111 | 0.90 | PDE3A (0.49) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL26247475 | 0.89 | PDE3A (0.50) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL18270531 | 0.85 | PDE3A (0.49) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL13713969 | 0.85 | PDE3A (0.62) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL2912374 | 0.85 | PDE3A (0.62) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL19932385 | 0.85 | PDE3A (0.62) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL12826168 | 0.85 | PDE3A (0.41) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL20403331 | 0.83 | PDE3A (0.49) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL18389736 | 0.83 | POLA1 (0.46) | PDE3APDE4DSLC29A1POLA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351551-B1 | PREPARATION METHOD OF NUCLEOSIDE PHOSPHORAMIDATE PRODRUGS AND INTERMEDIATES THEREOF | BRIGHTGENE BIO MEDICAL TECH CO LTD (CN) | 2022-12-07 | — | — | EP | disclosed |