Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25852329 | 0.91 | SLC1A3 (0.35) | RIPK1SLC1A3SLC1A2SLC1A1CYP1A2 | |
| SCHEMBL24736807 | 0.83 | RIPK1 (0.34) | RIPK1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25853553 | 0.82 | — | — | |
| SCHEMBL24736771 | 0.81 | RIPK1 (0.34) | RIPK1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL24736759 | 0.81 | RIPK1 (0.34) | RIPK1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22142945 | 0.78 | RIPK1 (0.35) | RIPK1SLC1A3SLC1A2SLC1A1CYP1A2 | |
| SCHEMBL23278543 | 0.77 | SLC1A3 (0.36) | RIPK1SLC1A3SLC1A2SLC1A1CYP1A2 | |
| SCHEMBL17719388 | 0.76 | RIPK1 (0.36) | RIPK1SLC1A3SLC1A2SLC1A1CYP1A2 | |
| SCHEMBL17719365 | 0.76 | RIPK1 (0.36) | RIPK1SLC1A3SLC1A2SLC1A1CYP1A2 | |
| SCHEMBL24736762 | 0.75 | RIPK1 (0.34) | RIPK1NTRK1NTRK2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221514-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | GILEAD SCIENCES, INC. (US) | 2022-10-20 | — | — | WO | disclosed |