Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.55 |
| ▸ | TK1 | P04183 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24737129 | 1.00 | RNASE1 (0.55) | RNASE1TK1ALDH1A1HTTLMNA | |
| SCHEMBL13871557 | 0.90 | RNASE1 (0.44) | RNASE1TK1ALDH1A1HTTLMNA | |
| SCHEMBL22992642 | 0.85 | POLB (0.45) | RNASE1POLBNPC1 | |
| SCHEMBL20879495 | 0.85 | POLB (0.45) | RNASE1POLBNPC1 | |
| SCHEMBL13871554 | 0.85 | NPC1 (0.39) | RNASE1TK1ALDH1A1HTTPOLB | |
| SCHEMBL22992494 | 0.81 | RNASE1 (0.60) | RNASE1TK1ALDH1A1HTTBCHE | |
| SCHEMBL5054200 | 0.81 | RNASE1 (0.60) | RNASE1TK1ALDH1A1HTTBCHE | |
| SCHEMBL4130043 | 0.80 | TYMS (0.46) | RNASE1ALDH1A1HTTLMNAPOLB | |
| SCHEMBL13871560 | 0.80 | TYMS (0.46) | RNASE1ALDH1A1HTTLMNAPOLB | |
| SCHEMBL5717548 | 0.80 | TYMS (0.46) | RNASE1ALDH1A1HTTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256490-A9 | IMPROVED SYNTHESIS OF PHOSPHORAMIDATES FOR THE TREATMENT OF HEPATITIS B VIRUS | Antios Therapeutics, Inc. (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2022256490-A2 | IMPROVED SYNTHESIS OF PHOSPHORAMIDATES FOR THE TREATMENT OF HEPATITIS B VIRUS | Antios Therapeutics, Inc. (US) | 2022-12-08 | — | — | WO | disclosed |