SCHEMBL247373

SCHEMBL247373

CCCCc1ccccc1OC(=O)Oc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.55
THRB P10828 1/20 0.55
PPARA Q07869 2/20 0.47
PPARG P37231 1/20 0.47
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
RECQL P46063 1/20 0.42
KMT2A Q03164 1/20 0.42
POLB P06746 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
LTB4R Q15722 1/20 0.41
LTB4R2 Q9NPC1 1/20 0.41
PPARD Q03181 1/20 0.41
ALOX5 P09917 1/20 0.41
PTGS2 P35354 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248389 0.95 THRA (0.60) THRATHRBPPARAPPARGLTB4R
SCHEMBL249213 0.94 THRA (0.63) THRATHRBPPARAPPARGLTB4R
SCHEMBL247205 0.94 THRA (0.63) THRATHRBPPARAPPARGLTB4R
SCHEMBL6245058 0.94 THRA (0.63) THRATHRBPPARAPPARGLTB4R
SCHEMBL5165577 0.94 THRA (0.63) THRATHRBPPARAPPARGLTB4R
SCHEMBL5166817 0.94 THRA (0.63) THRATHRBPPARAPPARGLTB4R
SCHEMBL728259 0.92 THRA (0.61) THRATHRBPPARAPPARGKDM4E
SCHEMBL29416629 0.92 THRA (0.61) THRATHRBPPARAPPARGKDM4E
SCHEMBL6119606 0.91 THRA (0.47) THRATHRBPPARAPPARGKDM4E
SCHEMBL1838972 0.89 THRA (0.58) THRATHRBPPARAPPARGKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174935-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED OPTICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-21 EP disclosed
EP-3174934-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-14 EP disclosed
EP-3227374-B1 COPOLYCARBONATE COMPOUNDS WITH IMPROVED RHEOLOGICAL AND OPTICAL PROPERTIES CONTAINING DIGLYCEROLESTER COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-06-01 EP disclosed
EP-3880474-A1 PLASTIC FILMS HAVING HIGH OPACITY AND LOW TRANSPARENCY FOR ID DOCUMENTS HAVING A TRANSPARENT WINDOW Covestro Intellectual Property GmbH & Co. KG (DE) 2021-09-22 EP disclosed
EP-3452530-B1 COPOLYCARBONATE AS SUPPORT MATERIAL FOR 3D PRINTING COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2020-09-30 EP disclosed
EP-3227387-B1 COPOLYCARBONATE COMPOUNDS WITH IMPROVED PROCESSABILITY CONTAINING PE WAXES COVESTRO DEUTSCHLAND AG (DE) 2020-03-11 EP disclosed
US-10323145-B2 Copolycarbonate compositions with cyclic and linear oligomers and improved optical properties COVESTRO DEUTSCHLAND AG (DE) 2019-06-18 US disclosed
US-20190143582-A1 COPOLYCARBONATE AS A SUPPORTING MATERIAL IN 3-D PRINTING COVESTRO DEUTSCHLAND AG (DE) 2019-05-16 US disclosed
EP-2496636-B1 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS COVESTRO DEUTSCHLAND AG (DE) 2019-05-15 EP disclosed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
US-20030027971-A1 Preparation of copolycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
EP-1277781-A2 Process for preparing copolycarbonates Bayer Aktiengesellschaft (DE) 2003-01-22 EP disclosed
EP-1270638-A2 Process and use of polyestercarbonates Bayer Aktiengesellschaft (DE) 2003-01-02 EP disclosed
EP-1266924-A2 Polycarbonates, polyestercarbonates and polyesters having branched endgroups BAYER AG (DE) 2002-12-18 EP disclosed
US-20020188091-A1 Process for continuous production of polycarbonates and a reactor therefor COVESTRO DEUTSCHLAND AG (DE) 2002-12-12 US disclosed
WO-2002085967-A1 METHOD FOR CONTINUOUSLY PRODUCING POLYCARBONATES ACCORDING TO THE MELT TRANSESTERIFICATION METHOD BAYER AKTIENGESELLSCHAFT (DE) 2002-10-31 WO disclosed
EP-1253163-A1 Process for continuously preparing polycarbonates by transesterification BAYER AG (DE) 2002-10-30 EP disclosed
WO-2002077066-A1 METHOD FOR PRODUCING OLIGOCARBONATES BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
WO-2002077067-A2 METHOD FOR PRODUCING POLYCARBONATES BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
US-20020137874-A1 Process for producing oligocarbonates COVESTRO DEUTSCHLAND AG (DE) 2002-09-26 US disclosed