Urea

Urea

SCHEMBL2473758

NC(N)=O.NC(N)=O.OO

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.86
ALDH1A1 P00352 4/20 0.86
TDP1 Q9NUW8 4/20 0.86
OR51E2 Q9H255 2/20 0.86
ACHE P22303 1/20 0.75
LDHA P00338 3/20 0.60
LDHB P07195 1/20 0.60
BLM P54132 5/20 0.50
PMP22 Q01453 4/20 0.50
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
ALOX15 P16050 2/20 0.50
CA1 P00915 1/20 0.50
CYP3A4 P08684 4/20 0.42
TSHR P16473 4/20 0.42
HSD17B10 Q99714 3/20 0.42
NFKB1 P19838 2/20 0.42
HPGD P15428 2/20 0.42
CYP1A2 P05177 2/20 0.42
THPO P40225 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL1439370 1.00
Urea SCHEMBL42148 1.00
Carbamic Acid SCHEMBL29871772 0.94 ACHE (0.88) LMNAALDH1A1TDP1OR51E2ACHE
Carbamic Acid SCHEMBL346553 0.94
Urea SCHEMBL3773707 0.94
Carbamic Acid SCHEMBL29832782 0.94 ACHE (0.88) LMNAALDH1A1TDP1OR51E2ACHE
Carbamic Acid SCHEMBL15671733 0.94 ACHE (0.88) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL10483615 0.94
Urea SCHEMBL12468842 0.94
Urea SCHEMBL4393055 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4577513-A1 PROCESS FOR DISTILLATIVE RECOVERY OF 1,1,1,3,3,3-HEXAFLUORO-2-PROPANOL (HFIP) FROM MIXTURES WITH 4- SUBSTITUTED 1,2,3,4-TETRAHYDROQUINOLINES Bayer Aktiengesellschaft (DE) 2025-07-02 EP disclosed
EP-4522614-A1 8- AND 6-SUBSTITUTED PYRIDOPYRIMIDINE DERIVATIVES AS KRAS INHIBITORS Beta Pharma, Inc. (US) 2025-03-19 EP disclosed
US-20240268379-A1 BIODEGRADABLE PVA/PVP HYDROGELS, USES AND PREPARATION THEREOF BAR ILAN UNIVERSITY (IL) 2024-08-15 US disclosed
CN-117368479-B Biomarker and detection kit for lung adenocarcinoma diagnosis 郑州大学 2024-07-02 CN disclosed
EP-4355095-A1 BIODEGRADABLE PVA/PVP HYDROGELS, USES AND PREPARATION THEREOF Bar-Ilan University (IL) 2024-04-24 EP disclosed
WO-2024041976-A1 PROCESS FOR DISTILLATIVE RECOVERY OF 1,1,1,3,3,3-HEXAFLUORO-2-PROPANOL (HFIP) FROM MIXTURES WITH 4- SUBSTITUTED 1,2,3,4-TETRAHYDROQUINOLINES BAYER AKTIENGESELLSCHAFT (DE) 2024-02-29 WO disclosed
WO-2022264149-A9 BIODEGRADABLE PVA/PVP HYDROGELS, USES AND PREPARATION THEREOF BAR-ILAN UNIVERSITY (IL) 2024-01-25 WO disclosed
WO-2023219941-A1 8- AND 6-SUBSTITUTED PYRIDOPYRIMIDINE DERIVATIVES AS KRAS INHIBITORS BETA PHARMA, INC. (US) 2023-11-16 WO disclosed
CN-115873022-A 2-oxothiazole derivatives as A2A inhibitors and compounds for the treatment of cancer 伊忒欧斯比利时股份公司 2023-03-31 CN disclosed
WO-2022264149-A1 BIODEGRADABLE PVA/PVP HYDROGELS, USES AND PREPARATION THEREOF BAR-ILAN UNIVERSITY (IL) 2022-12-22 WO disclosed
CN-103282016-A An aqueous stable composition for delivering substrates for a depilatory product using peracetic acid DU PONT 2013-09-04 CN disclosed
CN-103269680-A ENZYMATIC PERACID GENERATION FOR USE IN HAIR CARE PRODUCTS DU PONT 2013-08-28 CN disclosed
CN-103269679-A enzymatic peracid production for oral care products DU PONT 2013-08-28 CN disclosed
CN-103260597-A A non-aqueous stable composition for delivering substrates for a depilatory product using peracids DU PONT 2013-08-21 CN disclosed
EP-2371815-A1 Sythesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XenoPort, Inc. (US) 2011-10-05 EP disclosed
CN-102145005-A Cationic steroid antimicrobial compositions and methods of use UNIV VANDERBILT 2011-08-10 CN disclosed
CN-101378761-A Cationic steroid antimicrobial compositions and methods of use thereof UNIV BRIGHAM YOUNG (US) 2009-03-04 CN disclosed
CN-101203209-A Topical ungual formulations MEDPHARM LTD (GB) 2008-06-18 CN disclosed
US-4250124-A FIREPROOFING TEXTILES; REACTION OF AN HYDROXY-CONTAINING COMPOUND AND A 2-SUBSTITUTED-2-OXO-OXA-PHOSPHOLANE HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed
US-4220610-A Organic phosphorus compounds with 2-hydroxyalkyl-phosphonic acid groups HOECHST AKTIENGESELLSCHAFT (DE) 1980-09-02 US disclosed