SCHEMBL24738355

SCHEMBL24738355

c1ccc(-c2cccc(-c3ccc(-n4c5ccccc5c5ccccc54)c4c3oc3cc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)ccc34)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 3/20 0.34
ALOX5 P09917 1/20 0.31
TSHR P16473 1/20 0.31
MMP12 P39900 1/20 0.30
MMP13 P45452 1/20 0.30
CDC14B O60729 1/20 0.30
CDC14A Q9UNH5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24738382 1.00 PRKDC (0.34) PRKDCALOX5TSHRMMP12MMP13
SCHEMBL24738357 0.98 PRKDC (0.33) PRKDCALOX5TSHR
SCHEMBL24738728 0.98 PRKDC (0.32) PRKDCTSHRMMP12MMP13CDC14B
SCHEMBL24738651 0.95 CDC14B (0.34) PRKDCTSHRCDC14BCDC14A
SCHEMBL24738385 0.95 CDC14B (0.34) PRKDCTSHRCDC14BCDC14A
SCHEMBL24739309 0.94 CDC14B (0.32) PRKDCTSHRMMP12MMP13CDC14B
SCHEMBL24738692 0.94 CDC14B (0.34) PRKDCTSHRCDC14BCDC14A
SCHEMBL24739310 0.93 CDC14B (0.32) PRKDCTSHRMMP12MMP13CDC14B
SCHEMBL24738680 0.93 PRKDC (0.32) PRKDCTSHR
SCHEMBL25458840 0.92 PRKDC (0.36) PRKDCALOX5TSHRMMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220396568-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2022-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220396568-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE CYP1A1, CYP1B1, CRY1 PRKDC 4383/4885ALOX5 320/4885TSHR 4253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.