Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | HEXA | P06865 | 1/20 | 0.32 |
| ▸ | HEXB | P07686 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190811 | 0.88 | PLA2G7 (0.46) | PLA2G7HDAC6ALDH1A1RECQLKMT2A | |
| SCHEMBL11466101 | 0.84 | PLA2G7 (0.46) | PLA2G7HDAC6ALDH1A1RECQLKMT2A | |
| SCHEMBL4447273 | 0.80 | PLA2G7 (0.50) | PLA2G7HDAC6ALDH1A1RECQLKMT2A | |
| SCHEMBL25000505 | 0.79 | POLB (0.37) | PLA2G7HDAC6ALDH1A1RECQLKMT2A | |
| SCHEMBL7291993 | 0.78 | PLA2G7 (0.49) | PLA2G7HDAC6ALDH1A1RECQLKMT2A | |
| SCHEMBL22702280 | 0.78 | PLA2G7 (0.49) | PLA2G7HDAC6ALDH1A1RECQLKMT2A | |
| SCHEMBL8827200 | 0.78 | HDAC6 (0.37) | PLA2G7HDAC6KMT2AKDM4EHEXA | |
| SCHEMBL10969304 | 0.78 | PLA2G7 (0.49) | PLA2G7HDAC6ALDH1A1RECQLKMT2A | |
| SCHEMBL29303859 | 0.78 | HDAC6 (0.38) | PLA2G7HDAC6ALDH1A1KMT2AMEN1 | |
| SCHEMBL414553 | 0.77 | F2 (0.48) | PLA2G7HDAC6ALDH1A1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134629-A1 | NUCLEAR TRANSPORT REGULATOR AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |
| WO-2022197758-A1 | HETEROARYL INHIBITORS OF PLASMA KALLIKREIN | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2022-09-22 | — | — | WO | disclosed |