Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 19/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24739950 | 0.88 | METTL3 (0.42) | METTL3KLKB1 | |
| SCHEMBL24738215 | 0.84 | METTL3 (0.42) | METTL3KLKB1 | |
| SCHEMBL30997753 | 0.84 | METTL3 (0.42) | METTL3KLKB1 | |
| SCHEMBL29303167 | 0.84 | PDE2A (0.39) | METTL3KLKB1 | |
| SCHEMBL24738587 | 0.84 | METTL3 (0.42) | METTL3KLKB1 | |
| SCHEMBL24738586 | 0.84 | METTL3 (0.42) | METTL3KLKB1 | |
| SCHEMBL24739071 | 0.83 | METTL3 (0.43) | METTL3KLKB1 | |
| SCHEMBL24729671 | 0.79 | METTL3 (0.44) | METTL3KLKB1 | |
| SCHEMBL24737849 | 0.78 | KLKB1 (0.41) | METTL3KLKB1 | |
| SCHEMBL29136869 | 0.78 | KLKB1 (0.41) | METTL3KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022197758-A1 | HETEROARYL INHIBITORS OF PLASMA KALLIKREIN | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2022-09-22 | — | — | WO | disclosed |