Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 17/20 | 0.61 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | LCAT | P04180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24739240 | 0.88 | TIPARP (0.58) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL24739457 | 0.88 | TIPARP (0.58) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25220590 | 0.87 | TIPARP (0.67) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL24739463 | 0.86 | TIPARP (0.58) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL24739236 | 0.86 | TIPARP (0.58) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25698183 | 0.85 | TIPARP (0.73) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL24739450 | 0.85 | TIPARP (0.77) | TIPARPPARP14PARP12TNKS2PARP11 | |
| SCHEMBL24739449 | 0.85 | TIPARP (0.77) | TIPARPPARP14PARP12TNKS2PARP11 | |
| SCHEMBL25270498 | 0.85 | TIPARP (0.73) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25221394 | 0.85 | TIPARP (0.73) | TIPARPTNKSPARP14PARP10PARP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253101-A1 | PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR | 上海优理惠生医药有限公司 | 2022-12-08 | — | — | WO | disclosed |