Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 17/20 | 0.73 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | LCAT | P04180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25270498 | 0.97 | TIPARP (0.73) | TIPARPPARP1TNKSPARP14PARP10 | |
| SCHEMBL25221394 | 0.97 | TIPARP (0.73) | TIPARPPARP1TNKSPARP14PARP10 | |
| SCHEMBL25220590 | 0.94 | TIPARP (0.67) | TIPARPPARP1TNKSPARP14PARP10 | |
| SCHEMBL25697894 | 0.89 | TIPARP (0.62) | TIPARPPARP1LCAT | |
| SCHEMBL25697600 | 0.87 | TIPARP (0.60) | TIPARPPARP1TNKSPARP14PARP10 | |
| SCHEMBL24738980 | 0.86 | TIPARP (0.84) | TIPARPPARP1 | |
| SCHEMBL24739237 | 0.85 | TIPARP (0.61) | TIPARPPARP1TNKSPARP14PARP10 | |
| SCHEMBL24739049 | 0.84 | TIPARP (1.00) | TIPARP | |
| SCHEMBL24739458 | 0.84 | TIPARP (1.00) | TIPARP | |
| SCHEMBL25272747 | 0.84 | TIPARP (1.00) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183216-A1 | PYRIDIZIN-3(2H)-ONE DERIVATIVES | GILEAD SCIENCES, INC. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183216-A1 | PYRIDIZIN-3(2H)-ONE DERIVATIVES | PIR, CYP3A43, CYP1A2 | TIPARP 3487/4885PARP1 220/4885TNKS 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.