Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24739023 | 1.00 | GRIK1 (0.38) | GRIK1GRIA2HTR1ASLC6A2SLC6A3 | |
| SCHEMBL24739410 | 0.89 | GRIN1 (0.39) | GRIN1GRIN2BMAPTALDH1A1 | |
| SCHEMBL24739222 | 0.89 | GRIN1 (0.39) | GRIN1GRIN2BMAPTALDH1A1 | |
| SCHEMBL24739442 | 0.84 | KCNH2 (0.40) | GRIN1GRIN2BMAPTCYP1A2CYP2C9 | |
| SCHEMBL24739384 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTCYP4F2CYP4A11CYP1A2 | |
| SCHEMBL24739532 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTCYP4F2CYP4A11CYP1A2 | |
| SCHEMBL24739051 | 0.81 | S1PR3 (0.39) | GRIN1GRIN2BALDH1A1 | |
| SCHEMBL24739418 | 0.80 | HRH3 (0.43) | SLC6A2SLC6A3 | |
| SCHEMBL24739544 | 0.79 | EPHX2 (0.35) | GRIN1GRIN2BALDH1A1 | |
| SCHEMBL24739210 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2MAPTCYP4F2CYP4A11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253101-A1 | PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR | 上海优理惠生医药有限公司 | 2022-12-08 | — | — | WO | disclosed |