SCHEMBL24739655

SCHEMBL24739655

CCN(Cc1ccccc1)C(=O)C(Cc1ccccc1)N1C(=O)c2cc(Oc3ccc(OC[Si](OC)(OC)OC)cc3)c3c4c(Oc5ccc(OC[Si](OC)(OC)OC)cc5)cc5c6c(cc(Oc7ccc(OC[Si](OC)(OC)OC)cc7)c(c7c(Oc8ccc(OC[Si](OC)(OC)OC)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(Cc1ccccc1)C(=O)N(CC)Cc1ccccc1)C5=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 3/20 0.37
GAA P10253 1/20 0.37
LPAR1 Q92633 4/20 0.36
LPAR5 Q9H1C0 4/20 0.36
TRPM8 Q7Z2W7 1/20 0.36
AADAT Q8N5Z0 1/20 0.35
TSHR P16473 2/20 0.35
L3MBTL1 Q9Y468 4/20 0.35
TP53 P04637 1/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PPARG P37231 1/20 0.34
PPARD Q03181 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24739771 0.84 MAPT (0.38) POLBKMT2AMAPTNPSR1ALDH1A1
SCHEMBL24908692 0.81 POLB (0.42) POLBKMT2AMAPTNPSR1ALDH1A1
SCHEMBL24739825 0.80 POLB (0.40) POLBKMT2AMAPTNPSR1ALDH1A1
SCHEMBL24739795 0.80 POLB (0.40) POLBKMT2AMAPTNPSR1ALDH1A1
SCHEMBL24740194 0.79 POLB (0.37) POLBKMT2AMAPTNPSR1ALDH1A1
SCHEMBL24705178 0.79 POLB (0.37) POLBKMT2AMAPTNPSR1ALDH1A1
SCHEMBL24705469 0.79 HSD11B1 (0.43) POLBKMT2AMAPTNPSR1ALDH1A1
SCHEMBL24908691 0.77 HSD11B1 (0.46) POLBKMT2AMAPTNPSR1ALDH1A1
SCHEMBL24908666 0.76 POLB (0.47) POLBKMT2AMAPTALDH1A1GAA
SCHEMBL24908742 0.76 HSD11B1 (0.45) POLBKMT2AMAPTNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220390841-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2022-12-08 US disclosed