SCHEMBL24739733

SCHEMBL24739733

CO[Si](Cc1cccc(Oc2ccc(Oc3cc4c5c(cc(Oc6ccc(Oc7cccc(C[Si](OC)(OC)OC)c7)cc6)c6c7c(Oc8ccc(Oc9cccc(C[Si](OC)(OC)OC)c9)cc8)cc8c9c(cc(Oc%10ccc(Oc%11cccc(C[Si](OC)(OC)OC)c%11)cc%10)c(c3c56)c97)C(=O)N(C(C(=O)OCc3cccc5c3oc3ccccc35)C(C)C)C8=O)C(=O)N(C(C(=O)OCc3cccc5c3oc3ccccc35)C(C)C)C4=O)cc2)c1)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 2/20 0.33
HDAC8 Q9BY41 1/20 0.32
FAAH O00519 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24739728 0.83 TDP1 (0.35)
SCHEMBL24908670 0.77 HDAC8 (0.40) EDNRBHDAC8KDM4EMAPT
SCHEMBL24739679 0.75 USP2 (0.32) EDNRBMAPT
SCHEMBL24740228 0.74
SCHEMBL24739831 0.72 KDM4E (0.35) KDM4EMAPT
SCHEMBL24704922 0.70 FFAR1 (0.34) MAPT
SCHEMBL24739664 0.70 KMT2A (0.32) MAPT
SCHEMBL24908944 0.69 KDM4E (0.36) EDNRBHDAC8KDM4EMAPT
SCHEMBL24739616 0.68 LMNA (0.46) KDM4EMAPT
SCHEMBL24909099 0.67 MAPT (0.36) KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220390841-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2022-12-08 US disclosed