SCHEMBL24739749

SCHEMBL24739749

CC(C)c1cccc(C(C)C)c1OC(=O)COC(=O)CN(C)C

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SCN5A Q14524 1/20 0.47
SCN9A Q15858 1/20 0.47
SCN10A Q9Y5Y9 1/20 0.47
NLRP3 Q96P20 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23299323 0.89 SCN5A (0.40) SCN5ASCN9ASCN10ANLRP3
SCHEMBL24739761 0.89 SCN5A (0.40) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299366 0.84 SCN5A (0.49) SCN5ASCN9ASCN10ANLRP3
SCHEMBL24740676 0.83 SCN5A (0.46) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299322 0.83 SCN5A (0.47) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299358 0.83 SCN5A (0.47) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299354 0.83 SCN5A (0.47) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299307 0.82 SCN5A (0.46) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299339 0.82 SCN5A (0.53) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299362 0.82 SCN5A (0.46) SCN5ASCN9ASCN10ANLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220388947-A1 Nitrogen-containing Derivative of Substituted Phenol Hydroxy Acid Ester, and Preparation and Use Thereof WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388947-A1 Nitrogen-containing Derivative of Substituted Phenol Hydroxy Acid Ester, and Preparation and Use Thereof EGLN2, EGLN3, HPD SCN5A 788/4885SCN9A 513/4885SCN10A 463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.