Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 11/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24739041 | 1.00 | TIPARP (0.64) | TIPARPCHRM2CHRM1KDM4EPOLB | |
| SCHEMBL24739385 | 0.93 | TIPARP (0.54) | TIPARPCHRM2CHRM1 | |
| SCHEMBL24739383 | 0.86 | TIPARP (0.47) | TIPARPCHRM2CHRM1CHRM3 | |
| SCHEMBL24739046 | 0.86 | TIPARP (0.42) | TIPARP | |
| SCHEMBL24740459 | 0.86 | TIPARP (0.42) | TIPARP | |
| SCHEMBL28915016 | 0.84 | TIPARP (0.72) | TIPARPCHRM2CHRM1 | |
| SCHEMBL28915019 | 0.84 | TIPARP (0.72) | TIPARPCHRM2CHRM1 | |
| SCHEMBL24740461 | 0.81 | POLB (0.39) | TIPARPKDM4EPOLB | |
| SCHEMBL24739045 | 0.81 | POLB (0.39) | TIPARPKDM4EPOLB | |
| SCHEMBL25272747 | 0.78 | TIPARP (1.00) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253101-A1 | PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR | 上海优理惠生医药有限公司 | 2022-12-08 | — | — | WO | disclosed |