Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | HBB | P68871 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411806 | 0.88 | APP (0.59) | APPRELAHSD17B3PTGS1MAPT | |
| SCHEMBL10411804 | 0.88 | APP (0.59) | APPRELAHSD17B3PTGS1MAPT | |
| SCHEMBL22359184 | 0.86 | APP (0.57) | APPRELAHSD17B3PTGS1MAPT | |
| SCHEMBL9967773 | 0.81 | APP (0.59) | APPRELAHSD17B3PTGS1MAPT | |
| SCHEMBL11971034 | 0.80 | APP (0.50) | APPRELAHSD17B3PTGS1MAPT | |
| SCHEMBL11971035 | 0.80 | APP (0.50) | APPRELAHSD17B3PTGS1MAPT | |
| SCHEMBL7915381 | 0.79 | RELA (0.81) | APPRELAHSD17B3PTGS1MAPT | |
| SCHEMBL1714446 | 0.79 | RELA (0.81) | APPRELAHSD17B3PTGS1MAPT | |
| SCHEMBL13467434 | 0.79 | RELA (0.81) | APPRELAHSD17B3PTGS1MAPT | |
| SCHEMBL3025040 | 0.79 | RELA (0.81) | APPRELAHSD17B3PTGS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220259490-A1 | LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME | Alliance for Energy Innovation, LLC | 2022-08-18 | — | — | US | disclosed |