Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 6/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24741859 | 0.84 | CA12 (0.50) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL24741781 | 0.78 | CA12 (0.50) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL30817313 | 0.77 | CA12 (0.48) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL24742540 | 0.74 | LTB4R (0.51) | CKS1BSKP1SKP2SUCNR1CA12 | |
| SCHEMBL6503304 | 0.73 | PTPN1 (0.48) | CA12CA1CA2CA9 | |
| SCHEMBL24743050 | 0.73 | CA12 (0.45) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL22280882 | 0.72 | CA12 (0.49) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL19979808 | 0.71 | CA12 (0.53) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL24920672 | 0.71 | CA12 (0.67) | SUCNR1CA12CA1CA2CA9 | |
| SCHEMBL2082274 | 0.71 | CYP3A4 (0.47) | CKS1BSKP1SKP2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206888-A1 | CDK2 INHIBITORS AND USE THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-10-06 | — | — | WO | disclosed |