SCHEMBL24742152

SCHEMBL24742152

Clc1cccc(-c2ccc3sc4cccc(N(c5ccccc5)c5ccccc5)c4c3c2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.37
PIM3 Q86V86 1/20 0.37
PIM2 Q9P1W9 1/20 0.37
KDM4E B2RXH2 1/20 0.37
PGR P06401 1/20 0.36
ALOX5 P09917 1/20 0.34
JAK2 O60674 1/20 0.34
LIMK1 P53667 2/20 0.34
MAP4K4 O95819 3/20 0.33
TAAR1 Q96RJ0 2/20 0.33
SLC9A1 P19634 1/20 0.33
BACE1 P56817 1/20 0.32
ESR2 Q92731 1/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22146887 0.88 KDM4E (0.48) PIM1KDM4EJAK2MAOB
SCHEMBL20871600 0.84 KDM4E (0.40) KDM4ETP53RAB9ASMN1; SMN2MAOB
SCHEMBL24883205 0.83 APP (0.35) PIM3KDM4ELIMK1
SCHEMBL24741770 0.83 GPR3 (0.33) PIM3LIMK1RAB9ASMN1; SMN2
SCHEMBL21398871 0.82 GPR3 (0.33) KDM4ELIMK1MAOB
SCHEMBL23314322 0.81 GPR3 (0.34) PIM3ALOX5RAB9ASMN1; SMN2
SCHEMBL24472040 0.81 GPR3 (0.37) NPC1TSHRRAB9ASMN1; SMN2MAOB
SCHEMBL23765164 0.81 PTGDR2 (0.36) KDM4ELIMK1
SCHEMBL24472632 0.81 GPR3 (0.34) PIM3ALOX5LIMK1RAB9ASMN1; SMN2
SCHEMBL24472044 0.81 GPR3 (0.34) PIM3ALOX5LIMK1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022255606-A1 COMPOUND FOR QUANTUM DOT LIGHT EMITTING ELEMENT, QUANTUM DOT LIGHT EMITTING ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2022-12-08 WO disclosed