SCHEMBL24742913

SCHEMBL24742913

CCOC(=O)NC(C)(C)[C@H](C)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.39
GAA P10253 3/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
LMNA P02545 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 1/20 0.36
PIK3CD O00329 1/20 0.36
NPC1 O15118 1/20 0.36
TSHR P16473 1/20 0.36
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 2/20 0.34
PKM P14618 2/20 0.34
KMT2A Q03164 1/20 0.34
THRB P10828 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9476910 0.74 GAA (0.46) GAAMGAMSIMGAM2LMNA
SCHEMBL2757934 0.74 GAA (0.46) GAAMGAMSIMGAM2LMNA
SCHEMBL28787095 0.74 TSHR (0.45) MMP8GAAMGAMSIMGAM2
SCHEMBL27013740 0.74 MMP8 (0.40) MMP8GAAMGAMSIMGAM2
SCHEMBL27996452 0.73 GAA (0.44) GAAMGAMSIMGAM2LMNA
SCHEMBL9117578 0.73 GAA (0.44) GAAMGAMSIMGAM2LMNA
SCHEMBL3600424 0.72 MMP8 (0.38) MMP8GAAMGAMSIMGAM2
SCHEMBL1921481 0.72 MMP8 (0.38) MMP8GAAMGAMSIMGAM2
SCHEMBL3600427 0.72 MMP8 (0.38) MMP8GAAMGAMSIMGAM2
SCHEMBL10623261 0.71 GAA (0.42) GAAMGAMSIMGAM2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022258704-A1 HYBRID UV-LED RADIATION CURABLE PROTECTIVE VARNISHES FOR SECURITY DOCUMENTS SICPA HOLDING SA (CH) 2022-12-15 WO disclosed