Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 7/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 3/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | GIPR | P48546 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24743112 | 0.86 | RET (0.40) | NTRK1AURKAAURKB | |
| SCHEMBL24742405 | 0.83 | RET (0.39) | NTRK1NTRK3NTRK2AURKAAURKB | |
| SCHEMBL24742406 | 0.78 | AURKA (0.43) | AURKAAURKB | |
| SCHEMBL24742045 | 0.73 | KIT (0.36) | CTSA | |
| SCHEMBL24741941 | 0.72 | PLK4 (0.39) | NTRK1AURKAAURKBTNIK | |
| SCHEMBL24742307 | 0.72 | AURKA (0.40) | AURKAAURKB | |
| SCHEMBL24743111 | 0.70 | RET (0.47) | AURKA | |
| SCHEMBL24743108 | 0.70 | HDAC3 (0.45) | AURKA | |
| SCHEMBL24743066 | 0.69 | HDAC3 (0.44) | AURKASYK | |
| SCHEMBL24741818 | 0.69 | AURKA (0.44) | NTRK3NTRK2AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206888-A1 | CDK2 INHIBITORS AND USE THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-10-06 | — | — | WO | disclosed |