Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 2/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24742555 | 0.83 | NQO2 (0.44) | NQO2BCHEKDM4EL3MBTL1CA1 | |
| SCHEMBL24742258 | 0.81 | PTPN11 (0.40) | KDM4ANQO2BCHEMEN1NPC1 | |
| SCHEMBL24743050 | 0.81 | CA12 (0.45) | NQO2BCHECA1CA2 | |
| SCHEMBL26697003 | 0.80 | NPSR1 (0.47) | KDM4ANQO2BCHEKDM4EL3MBTL1 | |
| SCHEMBL24742308 | 0.75 | BCHE (0.45) | LATS1KDM4ANQO2BCHEKDM4E | |
| SCHEMBL1247884 | 0.74 | KCNH2 (0.38) | LATS1LATS2 | |
| SCHEMBL24741858 | 0.74 | CA1 (0.43) | NQO2BCHEMEN1GAAKMT2A | |
| SCHEMBL24742348 | 0.73 | CYP3A4 (0.47) | KDM4ANQO2BCHEMEN1NPC1 | |
| SCHEMBL24741977 | 0.73 | MAOA (0.43) | FPR3FPR2KDM4ANQO2BCHE | |
| SCHEMBL22306005 | 0.71 | AURKB (0.46) | KDM4ANQO2BCHENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206888-A1 | CDK2 INHIBITORS AND USE THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-10-06 | — | — | WO | disclosed |