Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1302135 | 0.91 | MET (0.56) | MET | |
| SCHEMBL3634219 | 0.89 | MET (0.52) | MET | |
| SCHEMBL12102858 | 0.87 | MET (0.51) | MET | |
| SCHEMBL2479041 | 0.86 | MET (0.54) | MET | |
| SCHEMBL16087481 | 0.86 | MET (0.59) | MET | |
| SCHEMBL1301308 | 0.85 | MET (0.62) | MET | |
| SCHEMBL27930497 | 0.82 | MET (0.54) | MET | |
| SCHEMBL13089764 | 0.81 | MET (0.49) | MET | |
| SCHEMBL1301325 | 0.81 | MET (0.56) | MET | |
| SCHEMBL18202439 | 0.80 | MET (0.56) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373647-B1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-2373647-A1 | PYRIDAZINONE DERIVATIVES | Merck Patent GmbH (DE) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010078909-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-07-15 | — | — | WO | disclosed |