SCHEMBL24745015

SCHEMBL24745015

CC1(C)c2cc(-c3ccc4ccccc4c3)ccc2-c2c(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccccc4)cc3)ccc3cccc1c23

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.34
LIPG Q9Y5X9 1/20 0.34
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
ESR1 P03372 3/20 0.33
ESR2 Q92731 3/20 0.33
CHRNB2 P17787 2/20 0.32
CHRNB4 P30926 2/20 0.32
CHRNA3 P32297 2/20 0.32
CHRNA4 P43681 2/20 0.32
CHRNA1 P02708 1/20 0.32
CHRNG P07510 1/20 0.32
CHRNB1 P11230 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
CHRND Q07001 1/20 0.32
PDK2 Q15119 2/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24745018 0.99 LPL (0.34) LPLLIPGHSD17B1HSD17B2ESR1
SCHEMBL24745022 0.98 LPL (0.33) LPLLIPGHSD17B1HSD17B2ESR1
SCHEMBL24744210 0.97 LPL (0.32) LPLLIPGHSD17B1HSD17B2PDK2
SCHEMBL24744176 0.96 PDK2 (0.34) PDK2PGR
SCHEMBL24744173 0.96 PDK2 (0.34) PDK2PGR
SCHEMBL24744168 0.95 PDK2 (0.33) PDK2PGR
SCHEMBL24745020 0.95 LPL (0.33) LPLLIPGHSD17B1HSD17B2ESR1
SCHEMBL24745014 0.95 PDK2 (0.34) LPLLIPGHSD17B1HSD17B2CHRNB2
SCHEMBL24744162 0.94 PDK2 (0.34) PDK2PGR
SCHEMBL24744608 0.93 PDK2 (0.37) PDK2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022260240-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2022-12-15 WO disclosed