Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.72 |
| ▸ | BRD4 | O60885 | 2/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.57 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560869 | 0.85 | CRBN (0.77) | CRBNBRD4DDB1IKZF3KDM4E | |
| SCHEMBL17169744 | 0.84 | CRBN (1.00) | CRBNBRD4DDB1IKZF3KDM4E | |
| SCHEMBL29923298 | 0.84 | CRBN (1.00) | CRBNBRD4DDB1IKZF3KDM4E | |
| Hydrochloric Acid SCHEMBL19359358 | 0.83 | CRBN (0.97) | CRBNBRD4DDB1IKZF3KDM4E | |
| SCHEMBL4781353 | 0.82 | CRBN (0.77) | CRBNBRD4DDB1IKZF3KDM4E | |
| SCHEMBL26646479 | 0.82 | CRBN (0.77) | CRBNBRD4DDB1IKZF3KDM4E | |
| SCHEMBL17834441 | 0.82 | CRBN (0.72) | CRBNBRD4DDB1IKZF3 | |
| SCHEMBL4778581 | 0.81 | CRBN (0.73) | CRBNBRD4DDB1IKZF3ALDH1A1 | |
| SCHEMBL8245437 | 0.81 | CRBN (0.74) | CRBNBRD4DDB1IKZF3KDM4E | |
| SCHEMBL3648191 | 0.80 | CRBN (0.70) | CRBNBRD4DDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |