⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11011491 | 0.79 | — | — | |
| SCHEMBL2722613 | 0.76 | — | — | |
| SCHEMBL2722611 | 0.76 | — | — | |
| SCHEMBL14382366 | 0.76 | — | — | |
| SCHEMBL164848 | 0.72 | — | — | |
| SCHEMBL12824734 | 0.71 | — | — | |
| SCHEMBL24869232 | 0.71 | — | — | |
| SCHEMBL316456 | 0.69 | — | — | |
| SCHEMBL15161704 | 0.69 | — | — | |
| SCHEMBL23894392 | 0.69 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |