Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.52 |
| ▸ | MAOA | P21397 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PYCR1 | P32322 | 5/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474560 | 1.00 | MAOB (0.52) | MAOBMAOACYP1A2TSHRADRA2A | |
| SCHEMBL2477504 | 0.90 | MAOB (0.53) | MAOBMAOACYP1A2TSHRADRA2A | |
| SCHEMBL2477505 | 0.90 | MAOB (0.53) | MAOBMAOACYP1A2TSHRADRA2A | |
| SCHEMBL2477506 | 0.90 | MAOB (0.53) | MAOBMAOACYP1A2TSHRADRA2A | |
| SCHEMBL2474342 | 0.82 | MAOB (0.60) | MAOBMAOACYP1A2TSHRADRA2A | |
| SCHEMBL2474070 | 0.82 | MAOB (0.60) | MAOBMAOACYP1A2TSHRADRA2A | |
| SCHEMBL2474314 | 0.82 | MAOB (0.60) | MAOBMAOACYP1A2TSHRADRA2A | |
| SCHEMBL18756729 | 0.80 | MAOB (0.58) | MAOBMAOACYP1A2TSHRADRA2A | |
| SCHEMBL2474429 | 0.73 | MAOB (0.57) | MAOBTSHRPKMMAPK1KDM4E | |
| SCHEMBL2474432 | 0.73 | MAOB (0.57) | MAOBTSHRPKMMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388245-A1 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | Bayer Pharma AG (DE) | 2011-11-23 | — | — | EP | disclosed |
| US-20110254522-A1 | STANDBY POWER SUPPLY CIRCUIT | HON HAI PRECISION INDUSTRY CO., LTD. (TW) | 2011-10-20 | — | — | US | disclosed |
| EP-2374779-A1 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | Bayer Pharma Aktiengesellschaft (DE) | 2011-10-12 | — | — | EP | disclosed |