Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 3/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.41 |
| ▸ | GRAMD1A | Q96CP6 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744625 | 0.91 | MCL1 (0.49) | PDE6D | |
| SCHEMBL24745172 | 0.90 | PDE6D (0.46) | PDE6DSTAT3ALKGRAMD1APTK2 | |
| SCHEMBL30000763 | 0.87 | MCL1 (0.51) | — | |
| SCHEMBL24745295 | 0.87 | MCL1 (0.51) | — | |
| SCHEMBL30000785 | 0.86 | DDB1 (0.45) | PDE6DGRAMD1A | |
| SCHEMBL24744714 | 0.86 | DDB1 (0.45) | PDE6DGRAMD1A | |
| SCHEMBL30000842 | 0.86 | MCL1 (0.50) | — | |
| SCHEMBL24744736 | 0.86 | MCL1 (0.50) | — | |
| SCHEMBL24744722 | 0.86 | GRAMD1A (0.45) | PDE6DSTAT3GRAMD1A | |
| SCHEMBL30000748 | 0.86 | GRAMD1A (0.45) | PDE6DSTAT3GRAMD1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |