Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL623790 | 0.98 | HPGD (0.55) | KMT2AMEN1SIGMAR1HPGDHSD11B1 | |
| SCHEMBL19088583 | 0.86 | HPGD (0.62) | KMT2AMEN1HPGDHSD11B1ALDH1A1 | |
| SCHEMBL12183401 | 0.86 | HPGD (0.67) | KMT2AMEN1HPGDHSD11B1ALDH1A1 | |
| SCHEMBL12311741 | 0.86 | HPGD (0.65) | SIGMAR1HPGDHSD11B1ALDH1A1TSHR | |
| SCHEMBL27986249 | 0.86 | KMT2A (0.67) | KMT2AMEN1SIGMAR1HPGDHSD11B1 | |
| SCHEMBL28114887 | 0.84 | KMT2A (0.65) | KMT2AMEN1SIGMAR1HPGDHSD11B1 | |
| SCHEMBL19088580 | 0.84 | HPGD (0.68) | KMT2AMEN1HPGDALDH1A1TSHR | |
| SCHEMBL13344996 | 0.83 | KMT2A (0.77) | KMT2AMEN1HPGDHSD11B1ALDH1A1 | |
| SCHEMBL623354 | 0.83 | POLB (0.57) | KMT2AMEN1HPGDHSD11B1ALDH1A1 | |
| SCHEMBL10194842 | 0.82 | HPGD (0.71) | KMT2AMEN1HPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |