Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27986249 | 0.98 | KMT2A (0.67) | KMT2AMEN1HSD11B1SIGMAR1HPGD | |
| SCHEMBL24746207 | 0.84 | KMT2A (0.54) | KMT2AMEN1HSD11B1SIGMAR1HPGD | |
| SCHEMBL1018987 | 0.84 | SIGMAR1 (0.53) | KMT2AMEN1HSD11B1SIGMAR1HPGD | |
| Hydrochloric Acid SCHEMBL623790 | 0.83 | HPGD (0.55) | KMT2AMEN1HSD11B1SIGMAR1HPGD | |
| SCHEMBL421902 | 0.83 | KMT2A (0.73) | KMT2AMEN1HSD11B1HPGDALDH1A1 | |
| SCHEMBL2655426 | 0.83 | KMT2A (0.73) | KMT2AMEN1HSD11B1HPGDALDH1A1 | |
| SCHEMBL29944147 | 0.81 | MEN1 (0.71) | KMT2AMEN1HSD11B1HPGDALDH1A1 | |
| SCHEMBL226167 | 0.81 | SIGMAR1 (0.56) | KMT2AMEN1SIGMAR1HPGDTDO2 | |
| SCHEMBL8358137 | 0.80 | SIGMAR1 (0.81) | SIGMAR1HPGDALDH1A1MKNK1MKNK2 | |
| SCHEMBL2004712 | 0.80 | KMT2A (0.69) | KMT2AMEN1HSD11B1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104262263-B | N,6 diphenylpyrimidine-4-amine Bcr-Abl inhibitors as well as preparation method and application thereof | 西安交通大学 | 2017-01-11 | — | — | CN | disclosed |