Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474635 | 0.95 | UTS2R (0.50) | UTS2RNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL2472852 | 0.90 | NPC1 (0.47) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL4227992 | 0.89 | HDAC3 (0.42) | UTS2RNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL2476312 | 0.89 | NPC1 (0.49) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL3834611 | 0.89 | KMT2A (0.48) | UTS2RNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL3836235 | 0.88 | NPC1 (0.48) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL4388403 | 0.87 | NPC1 (0.47) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL2478122 | 0.87 | UTS2R (0.42) | UTS2RNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL2476829 | 0.86 | UTS2R (0.49) | UTS2RSMN1; SMN2MAPTHDAC1HDAC3 | |
| SCHEMBL2478981 | 0.85 | NPC1 (0.42) | NPC1RAB9ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-B1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |