Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474633 | 0.89 | UTS2R (0.45) | HDAC3HDAC1UTS2RNPC1RAB9A | |
| SCHEMBL3218944 | 0.88 | NPC1 (0.40) | UTS2RNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL3230138 | 0.87 | UTS2R (0.47) | HDAC3HDAC1UTS2RHDAC8HDAC2 | |
| SCHEMBL2385454 | 0.86 | UTS2R (0.45) | HDAC3HDAC1UTS2RHDAC8HDAC2 | |
| SCHEMBL2386741 | 0.86 | HDAC3 (0.43) | HDAC3HDAC1UTS2RHDAC8NPC1 | |
| SCHEMBL4224028 | 0.86 | UTS2R (0.43) | HDAC3HDAC1UTS2RHDAC8SMN1; SMN2 | |
| SCHEMBL2384389 | 0.85 | HDAC1 (0.47) | HDAC3HDAC1UTS2RHDAC8HDAC2 | |
| SCHEMBL2385632 | 0.85 | UTS2R (0.43) | HDAC3HDAC1UTS2RHDAC8HDAC2 | |
| SCHEMBL3229763 | 0.84 | HDAC1 (0.47) | HDAC3HDAC1UTS2RHDAC8NPC1 | |
| SCHEMBL2384770 | 0.84 | UTS2R (0.54) | HDAC3HDAC1UTS2RHDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |