Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 14/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30316576 | 1.00 | CDK4 (0.44) | CDK4CCND1TYK2MAPK7TTK | |
| SCHEMBL24747223 | 0.91 | TYK2 (0.46) | CDK4CCND1TYK2TTKMAP4K1 | |
| SCHEMBL30316297 | 0.91 | TYK2 (0.46) | CDK4CCND1TYK2TTKMAP4K1 | |
| SCHEMBL29892159 | 0.90 | TYK2 (0.45) | CDK4CCND1TYK2TTKMAP4K1 | |
| SCHEMBL24746100 | 0.90 | TYK2 (0.45) | CDK4CCND1TYK2TTKMAP4K1 | |
| SCHEMBL24747219 | 0.85 | TYK2 (0.44) | CDK4CCND1TYK2MAPK7TTK | |
| SCHEMBL30316229 | 0.85 | TYK2 (0.44) | CDK4CCND1TYK2MAPK7TTK | |
| SCHEMBL24745826 | 0.84 | TYK2 (0.47) | CDK4CCND1TYK2MAP4K1LRRK2 | |
| SCHEMBL29891142 | 0.84 | TYK2 (0.47) | CDK4CCND1TYK2MAP4K1LRRK2 | |
| SCHEMBL24745891 | 0.83 | TYK2 (0.46) | CDK4CCND1TYK2MAPK7TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |