Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ITK | Q08881 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14801 | 0.78 | NPC1 (0.49) | LMNATP53ALOX15TSHRNPC1 | |
| SCHEMBL21538241 | 0.72 | NPC1 (0.40) | LMNATP53ALOX15TSHRITK | |
| SCHEMBL18968497 | 0.70 | KMT2A (0.46) | LMNATP53NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL11713011 | 0.67 | LMNA (0.84) | LMNATP53ALOX15TSHRKDM4E | |
| SCHEMBL18516680 | 0.65 | KMT2A (0.45) | LMNAALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14825161 | 0.63 | TSHR (0.77) | LMNATP53ALOX15TSHRNPC1 | |
| SCHEMBL26098997 | 0.62 | HSP90AA1 (0.66) | LMNATP53ALOX15TSHRHSP90AA1 | |
| SCHEMBL30032172 | 0.61 | HSP90AA1 (0.56) | LMNATP53ALOX15TSHRNPC1 | |
| SCHEMBL1222429 | 0.61 | LMNA (0.67) | LMNATP53ALOX15TSHRKDM4E | |
| SCHEMBL28462636 | 0.60 | BCL2A1 (0.46) | LMNATSHRKDM4EALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3561077-B1 | METHODS FOR CELL-PROLIFERATION-RELATED DISORDERS | SERVIER LAB (FR) | 2022-12-21 | — | — | EP | disclosed |