Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.68 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2477702 | 0.94 | MET (0.64) | METNQO2 | |
| SCHEMBL1317047 | 0.88 | MET (0.70) | METNQO2 | |
| SCHEMBL3084073 | 0.85 | MET (0.80) | METNQO2 | |
| SCHEMBL3079001 | 0.84 | MET (0.67) | METNQO2 | |
| SCHEMBL13152907 | 0.84 | MET (0.67) | METNQO2 | |
| SCHEMBL1581596 | 0.83 | MET (0.73) | METNQO2 | |
| SCHEMBL3089413 | 0.83 | MET (0.85) | METNQO2 | |
| Trifluoroacetic Acid SCHEMBL1320908 | 0.83 | MET (0.65) | METNQO2 | |
| Formic Acid SCHEMBL3100988 | 0.81 | MET (0.68) | METNQO2 | |
| SCHEMBL3087171 | 0.81 | MET (1.00) | METNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373644-B1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-10-24 | — | — | EP | claimed |
| EP-2373644-B1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2373644-A1 | PYRIDAZINONE DERIVATIVES | Merck Patent GmbH (DE) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010078910-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-07-15 | — | — | WO | disclosed |