SCHEMBL24748536

SCHEMBL24748536

c1ccc(-c2ccc(-c3cc4ccccc4c4ccccc34)cc2N(c2ccc(-c3cc4ccccc4c4ccccc34)cc2)c2cccc3c2sc2ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
CYP11B1 P15538 1/20 0.33
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
F9 P00740 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
MPI P34949 1/20 0.32
KMT2A Q03164 1/20 0.32
GPR84 Q9NQS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24749335 0.99 ALOX5 (0.39) ALOX5CYP11B1TNKSTNKS2F9
SCHEMBL24749332 0.99 ALOX5 (0.39) ALOX5CYP11B1TNKSTNKS2F9
SCHEMBL24748392 0.98 ALOX5 (0.39) ALOX5CYP11B1TNKSTNKS2F9
SCHEMBL24748126 0.97 ALOX5 (0.45) ALOX5CYP11B1TNKSTNKS2F9
SCHEMBL24749831 0.96 ALOX5 (0.39) ALOX5CYP11B1TNKSTNKS2F9
SCHEMBL24749835 0.95 ALOX5 (0.36) ALOX5CYP11B1
SCHEMBL24749832 0.95 ALOX5 (0.38) ALOX5CYP11B1F9KDM4EMEN1
SCHEMBL24750015 0.94 ALOX5 (0.41) ALOX5CYP11B1TNKSTNKS2F9
SCHEMBL24750033 0.94 ALOX5 (0.37) ALOX5CYP11B1TNKSTNKS2F9
SCHEMBL23258264 0.93 ALOX5 (0.41) ALOX5CYP11B1TNKSTNKS2F9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022259886-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE 出光興産株式会社 2022-12-15 WO disclosed