Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 15/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31694868 | 1.00 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL31694819 | 0.83 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL24751480 | 0.83 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL24749525 | 0.83 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL24750233 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL31009493 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL31694901 | 0.80 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL24751473 | 0.80 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL24750324 | 0.80 | TSHR (0.58) | MEN1KMT2AALDH1A1MAPTTHRB | |
| SCHEMBL31009353 | 0.79 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPTSCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022219246-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2022-10-20 | — | — | WO | disclosed |