Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.36 |
| ▸ | TUBB | P07437 | 3/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24751457 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL24751472 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL31694911 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL31694830 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL31694900 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL24749759 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL31694882 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL24749771 | 0.82 | PDE4A (0.43) | MAPTGAAHTT | |
| SCHEMBL24749768 | 0.82 | PDE4A (0.43) | MAPTGAAHTT | |
| SCHEMBL31694801 | 0.82 | PDE4A (0.43) | MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022219246-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2022-10-20 | — | — | WO | disclosed |