Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 2/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801539 | 0.95 | QPCT (0.47) | GSK3BQPCTPRNPCYP1A2CYP2C9 | |
| SCHEMBL21801481 | 0.91 | NPC1 (0.49) | GSK3BCYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL21801488 | 0.88 | CNR1 (0.46) | GSK3BQPCTNPSR1MAPTTP53 | |
| SCHEMBL21801673 | 0.83 | QPCT (0.47) | GSK3BQPCTNPSR1MAPTTP53 | |
| SCHEMBL21801522 | 0.82 | TDP1 (0.47) | CYP1A2CYP2C9CYP2C19MAPTNPC1 | |
| SCHEMBL21801489 | 0.81 | PRNP (0.40) | QPCTPRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21801473 | 0.81 | NPC1 (0.46) | GSK3BQPCTNPSR1NPC1RAB9A | |
| SCHEMBL21801469 | 0.80 | GSK3B (0.48) | GSK3BCYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL21801466 | 0.79 | MAPT (0.51) | CYP1A2CYP2C9CYP2C19NPSR1MAPT | |
| SCHEMBL21801477 | 0.79 | CDC7 (0.48) | QPCTPRNPCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220257569-A1 | INDOLE-OXADIAZOLE COMPOUNDS AND THEIR THERAPEUTIC USE | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2022-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220257569-A1 | INDOLE-OXADIAZOLE COMPOUNDS AND THEIR THERAPEUTIC USE | CNR2, GPR119, CNR1 | GSK3B 116/4885QPCT 2631/4885PRNP 4333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.