Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.72 |
| ▸ | CNR1 | P21554 | 9/20 | 0.72 |
| ▸ | ABHD12 | Q8N2K0 | 3/20 | 0.72 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.72 |
| ▸ | FAAH | O00519 | 2/20 | 0.72 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.72 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.72 |
| ▸ | LDHA | P00338 | 1/20 | 0.72 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.72 |
| ▸ | GPR183 | P32249 | 1/20 | 0.72 |
| ▸ | DRD3 | P35462 | 1/20 | 0.72 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.72 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.72 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.61 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.61 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11937352 | 0.86 | CNR2 (0.80) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL19410304 | 0.86 | CNR2 (0.80) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL21974430 | 0.86 | CNR2 (0.80) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL24134477 | 0.84 | CNR2 (0.78) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL31545781 | 0.84 | CNR2 (0.74) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL31544854 | 0.84 | CNR2 (0.74) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL31545351 | 0.84 | CNR2 (0.74) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL13394311 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL22705549 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL1227386 | 0.84 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9024093-B2 | Fluorination of organic compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-05-05 | — | — | US | disclosed |
| US-20110312903-A1 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2011-12-22 | — | — | US | disclosed |
| EP-2376408-A2 | FLUORINATION OF ORGANIC COMPOUNDS | President and Fellows of Harvard College (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010059943-A2 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312903-A1 | FLUORINATION OF ORGANIC COMPOUNDS | SLCO1B3, SLCO2B1, FLI1 | CNR2 2832/4885CNR1 2702/4885ABHD12 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.