Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.80 |
| ▸ | CNR1 | P21554 | 9/20 | 0.80 |
| ▸ | ABHD12 | Q8N2K0 | 3/20 | 0.80 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.80 |
| ▸ | FAAH | O00519 | 2/20 | 0.80 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.80 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.80 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.80 |
| ▸ | LDHA | P00338 | 1/20 | 0.80 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.80 |
| ▸ | GPR183 | P32249 | 1/20 | 0.80 |
| ▸ | DRD3 | P35462 | 1/20 | 0.80 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.80 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.80 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.68 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.68 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.68 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410304 | 1.00 | CNR2 (0.80) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL21974430 | 1.00 | CNR2 (0.80) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL4609 | 0.89 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL22705549 | 0.89 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL1227386 | 0.89 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL24702729 | 0.89 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL13394311 | 0.89 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL13214137 | 0.89 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH | |
| SCHEMBL2615500 | 0.89 | CNR2 (0.77) | CNR2CNR1ABHD12ABHD6FAAH | |
| Dronabinol SCHEMBL11375978 | 0.89 | CNR2 (1.00) | CNR2CNR1ABHD12ABHD6FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346952-A1 | CANNABINOID GLYCOSIDE PRODRUGS AND METHODS OF SYNTHESIS | GRAPHIUM BIOSCIENCES, INC. (US) | 2023-11-02 | — | — | US | disclosed |
| US-11667655-B2 | Silicon-based tetrahydrocannabinol derivatives and compositions thereof | GELEST, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| WO-2021163023-A1 | STABLE FORMULATIONS OF DRONABINOL | TRYAGx Labs Inc. (US) | 2021-08-19 | — | — | WO | disclosed |
| US-20170283391-A1 | CHIRAL SEPARATION OF delta8-THC, delta9-THC, AND RELATED ENANTIOMERS USING CO2-BASED CHROMATOGRAPHY | WATERS TECHNOLOGIES CORPORATION | 2017-10-05 | — | — | US | disclosed |
| US-20170283391-A1 | CHIRAL SEPARATION OF delta8-THC, delta9-THC, AND RELATED ENANTIOMERS USING CO2-BASED CHROMATOGRAPHY | WATERS TECHNOLOGIES CORPORATION | 2017-10-05 | — | — | US | disclosed |
| US-20170283391-A1 | CHIRAL SEPARATION OF delta8-THC, delta9-THC, AND RELATED ENANTIOMERS USING CO2-BASED CHROMATOGRAPHY | WATERS TECHNOLOGIES CORPORATION | 2017-10-05 | — | — | US | disclosed |
| WO-2017053574-A1 | CANNABINOID GLYCOSIDE PRODRUGS AND METHODS OF SYNTHESIS | VITALITY BIOPHARMA, INC. (US) | 2017-03-30 | — | — | WO | disclosed |
| EP-2215071-B1 | PRODRUGS OF TETRAHYDROCANNABINOL, COMPOSITIONS COMPRISING PRODRUGS OF TETRAHYDROCANNABINOL AND METHODS OF USING THE SAME | ZYNERBA PHARMACEUTICALS INC (US) | 2015-07-01 | — | — | EP | disclosed |
| US-8227627-B2 | Prodrugs of tetrahydrocannabinol, compositions comprising prodrugs of tetrahydrocannabinol and methods of using the same | ALLTRANZ INC. (US) | 2012-07-24 | — | — | US | disclosed |
| US-20090143462-A1 | Products of Tetrahydrocannabinol, Compositions Comprising Prodrugs of Tetrahydrocannabinol and Methods of Using the Same | ALLTRANZ (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283391-A1 | CHIRAL SEPARATION OF delta8-THC, delta9-THC, AND RELATED ENANTIOMERS USING CO2-BASED CHROMATOGRAPHY | CNR2, CNR1, GPR68 | CNR2 1/4885CNR1 2/4885ABHD12 812/4885 |
| US-20090143462-A1 | Products of Tetrahydrocannabinol, Compositions Comprising Prodrugs of Tetrahydrocannabinol and Methods of Using the Same | CNR2, CNR1, FAAH | CNR2 1/4885CNR1 2/4885ABHD12 1552/4885 |
| US-20230346952-A1 | CANNABINOID GLYCOSIDE PRODRUGS AND METHODS OF SYNTHESIS | CNR2, CNR1, UGCG | CNR2 1/4885CNR1 2/4885ABHD12 723/4885 |
| US-11667655-B2 | Silicon-based tetrahydrocannabinol derivatives and compositions thereof | CNR2, CNR1, SRI | CNR2 1/4885CNR1 2/4885ABHD12 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.