Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30138039 | 1.00 | ALDH1A1 (0.35) | ALDH1A1KMT2APDE4BPDE4APDE4C | |
| SCHEMBL1976614 | 0.89 | KMT2A (0.36) | ALDH1A1KMT2APDE4BPDE3B | |
| SCHEMBL30853071 | 0.87 | ALDH1A1 (0.32) | ALDH1A1KMT2A | |
| SCHEMBL30137942 | 0.87 | ALDH1A1 (0.32) | ALDH1A1KMT2A | |
| SCHEMBL24752020 | 0.87 | ALDH1A1 (0.32) | ALDH1A1KMT2A | |
| SCHEMBL30138073 | 0.87 | ALDH1A1 (0.32) | ALDH1A1KMT2A | |
| SCHEMBL24752018 | 0.85 | ALDH1A1 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL30067204 | 0.85 | ALDH1A1 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL12594627 | 0.77 | LCK (0.38) | ALDH1A1KMT2APDE4BPDE3B | |
| SCHEMBL29189646 | 0.75 | MEN1 (0.32) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881681-A | Substituted pyrrolo [2,3-d ] pyrimidines, their preparation and their therapeutic use | 赛诺菲 | 2024-04-12 | — | — | CN | disclosed |
| WO-2022263472-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-12-22 | — | — | WO | disclosed |
| EP-4105218-A1 | SUBSTITUTED PYRROLO[2,3-D] PYRIMIDINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-12-21 | — | — | EP | disclosed |