SCHEMBL2475314

SCHEMBL2475314

c1ccc(-c2nc(-c3nc(-c4ccccc4)c(-c4ccccc4)n3-c3ccccc3)n(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.67
ACHE P22303 1/20 0.67
MGAM O43451 5/20 0.52
GAA P10253 5/20 0.52
SI P14410 5/20 0.52
MGAM2 Q2M2H8 5/20 0.52
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2173277 0.94 BCHE (0.65) BCHEACHEMGAMGAASI
Bromide SCHEMBL28478160 0.92 BCHE (0.63) BCHEACHEMGAMGAASI
Phosphine SCHEMBL28534966 0.92 BCHE (0.63) BCHEACHEMGAMGAASI
SCHEMBL12854018 0.89 BCHE (0.68) BCHEACHEMGAMGAASI
SCHEMBL31050815 0.86 BCHE (0.57) BCHEACHEMGAMGAASI
SCHEMBL28939710 0.85 ESR1 (0.57) BCHEACHEMGAMGAASI
SCHEMBL14280142 0.85 BCHE (0.56) BCHEACHEMGAMGAASI
SCHEMBL11978720 0.85 BCHE (0.55) BCHEACHEMGAMGAASI
SCHEMBL12425052 0.84 BCHE (0.55) BCHEACHEMGAMGAASI
SCHEMBL14690332 0.84 BCHE (0.55) BCHEACHEMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1004687-A None JP disclosed
EP-2158620-B1 PIEZOCHROME COMPOSITE TOTALFOERSVARETS FORSKNINGSINS (SE) 2011-10-12 EP disclosed
US-7261680-B2 Stress and/or temperature-indicating composition for roll covers STOWE WOODWARD, L.L.C. (US) 2007-08-28 US disclosed
EP-1494848-A1 ROLL WITH STRESS AND/OR TEMPERATURE-INDICATING COVER Stowe Woodward, LLC. (US) 2005-01-12 EP disclosed
US-20030224917-A1 Stress and/or temperature-indicating composition for roll covers STOWE WOODWARD LLC 2003-12-04 US disclosed
WO-2003089227-A1 ROLL WITH STRESS AND/OR TEMPERATURE-INDICATING COVER STOWE WOODWARD, LLC (US) 2003-10-30 WO disclosed
EP-0530369-B1 CRYSTAL COMPRISING INDOLINOSPIROBENZOTHIOPYRAN DERIVATIVE AND RING-OPENING ISOMER THEREOF OTSUKA KAGAKU KK (JP) 1997-02-05 EP disclosed
US-5320784-A Crystal comprising an indolinospirobenzothiopyran derivative and its ring opened isomer OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1994-06-14 US disclosed
EP-0530369-A1 CRYSTAL COMPRISING INDOLINOSPIROBENZOTHIOPYRAN DERIVATIVE AND RING-OPENING ISOMER THEREOF OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1993-03-10 EP disclosed
JP-S644687-A METHOD OF CONTROLLING PHOTOCHROMIC REACTION SUMITOMO ELECTRIC INDUSTRIES 1989-01-09 JP disclosed
US-4634628-A Recording medium and image recording process CANON KABUSHIKI KAISHA (JP) 1987-01-06 US disclosed