Phosphine

Phosphine

SCHEMBL28534966

P.P.c1ccc(-c2nc(-c3ccccc3)n(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.63
ACHE P22303 1/20 0.63
MGAM O43451 4/20 0.50
GAA P10253 4/20 0.50
SI P14410 4/20 0.50
MGAM2 Q2M2H8 4/20 0.50
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HSP90AA1 P07900 1/20 0.45
MAPT P10636 1/20 0.45
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
AVPR1A P37288 1/20 0.43
HCAR1 Q9BXC0 1/20 0.43
PI4KA P42356 1/20 0.43
PI4K2B Q8TCG2 1/20 0.43
PI4K2A Q9BTU6 1/20 0.43
PI4KB Q9UBF8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2173277 0.98 BCHE (0.65) BCHEACHEMGAMGAASI
Bromide SCHEMBL28478160 0.96 BCHE (0.63) BCHEACHEMGAMGAASI
SCHEMBL2475314 0.92 BCHE (0.67) BCHEACHEMGAMGAASI
SCHEMBL31050815 0.90 BCHE (0.57) BCHEACHEMGAMGAASI
SCHEMBL28939710 0.89 ESR1 (0.57) BCHEACHEMGAMGAASI
SCHEMBL14280142 0.89 BCHE (0.56) BCHEACHEMGAMGAASI
SCHEMBL12425052 0.88 BCHE (0.55) BCHEACHEMGAMGAASI
SCHEMBL14690330 0.87 BCHE (0.55) BCHEACHEMGAMGAASI
SCHEMBL14690332 0.87 BCHE (0.55) BCHEACHEMGAMGAASI
SCHEMBL14280128 0.87 MGAM (0.55) BCHEACHEMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480175-A Green and efficient organic electrophosphorescent material with low-efficiency roll-off characteristic and preparation method thereof 吉林师范大学 2021-03-12 CN claimed
CN-112480175-A Green and efficient organic electrophosphorescent material with low-efficiency roll-off characteristic and preparation method thereof 吉林师范大学 2021-03-12 CN disclosed