Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 8/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 8/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 8/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 8/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 8/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2341600 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CRHBPCRHR2PSEN1PSEN2 | |
| SCHEMBL2335603 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CRHBPCRHR2PSEN1PSEN2 | |
| SCHEMBL2335394 | 0.89 | ALDH1A1 (0.64) | ALDH1A1CRHBPCRHR2PSEN1PSEN2 | |
| SCHEMBL2339742 | 0.84 | ALDH1A1 (0.58) | ALDH1A1CRHBPCRHR2PSEN1PSEN2 | |
| SCHEMBL2331482 | 0.81 | ALDH1A1 (0.83) | ALDH1A1CRHBPCRHR2PSEN1PSEN2 | |
| SCHEMBL2336734 | 0.80 | PSEN1 (0.63) | ALDH1A1CRHBPCRHR2PSEN1PSEN2 | |
| SCHEMBL2336091 | 0.79 | ALDH1A1 (0.66) | ALDH1A1CRHBPCRHR2PSEN1PSEN2 | |
| SCHEMBL2337725 | 0.79 | ALDH1A1 (0.70) | ALDH1A1CRHBPCRHR2PSEN1PSEN2 | |
| SCHEMBL2338436 | 0.75 | PSEN1 (0.56) | ALDH1A1CRHBPCRHR2PSEN1PSEN2 | |
| SCHEMBL2338044 | 0.74 | PSEN1 (0.50) | ALDH1A1CRHBPCRHR2PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374792-A1 | N-substituted benzene sulfonamides | Elan Pharmaceuticals Inc. (US) | 2011-10-12 | — | — | EP | disclosed |